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KMID : 0361020230660060387
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Korean Journal of Otolaryngology - Head and Neck Surgery
2023 Volume.66 No. 6 p.387 ~ p.392
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Characteristics of Patients With Severe Obstructive Sleep Apnea Who Maintain Slow-Wave Sleep
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Kim Min-Woo
Choi Myoung-Su
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Abstract
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Background and Objectives Obstructive sleep apnea (OSA) is a complex sleep-related re-spiratory disorder with various pathophysiology and clinical manifestations. Diagnosis andtreatment considering only the number of respiratory events, such as sleep duration, may havelimitations. The purpose of this study is to analyze the clinical and polysomnography (PSG)characteristics of patients with severe OSA in whom slow wave sleep (SWS) was well-main-tained.
Subjects and Method This study retrospectively analyzed 203 patients who underwentPSG due to suspected OSA. Severe OSA patients were classified into a SWS maintainedgroup (SWS≥15%) and a SWS reduced group (SWS<15%), and their clinical records, PSG re-sults, and heart rate variability (HRV) were compared.
Results The SWS maintained group (n=27), compared to the SWS reduced group (n=58),had a significantly longer total sleep time ( p=0.027) and lower wake after sleep onset ( p=0.001), rapid eye movoement (REM) latency ( p=0.007), non-supine apnea-hypopnea index(A HI, p=0.006), non-REM AHI ( p<0.001), arousal index ( p<0.001) and Epworth SleepinessScale ( p=0.048). In addition, the SWS maintained group had a significantly low value in verylow frequency in HRV than that of the SWS reduced group ( p=0.046).
Conclusion The SWS maintained group in the severe OSA showed better PSG and HRV re-sults and reduced daytime sleepiness than those of the SWS reduced group.
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KEYWORD
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Obstructive sleep apnea, Polysomnography, Sleepiness, Slow wave sleep
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